Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7849.017 | 0.9357 | 0.6515 | 0.3471 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7849.017 | 0.6092 | -0.5204 | 0.3471 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7849.017 | 0.2305 | -0.9708 | 0.3471 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7849.017 | 0.0056 | -1.0000 | 0.3471 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9421.021 | 0.9813 | 0.9010 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9421.021 | 0.9964 | 0.9806 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9421.021 | 1.0496 | 1.2774 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9421.021 | 1.0206 | 1.1126 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9421.021 | 1.0061 | 1.0330 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9421.021 | 0.8595 | 0.3320 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9421.021 | 0.4178 | -0.8078 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9421.021 | 0.1347 | -0.9908 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9421.021 | 0.0184 | -1.0000 | 0.3726 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7853.017 | 1.0215 | 1.0247 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7853.017 | 0.9705 | 0.9658 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7853.017 | 1.0288 | 1.0329 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7853.017 | 0.9878 | 0.9859 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7853.017 | 1.0226 | 1.0259 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7853.017 | 0.8861 | 0.8655 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7853.017 | 0.5189 | 0.3711 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7853.017 | 0.0481 | -0.6511 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7853.017 | 0.0735 | -0.5548 | 1.7375 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10056.021 | 0.9791 | 0.9528 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10056.021 | 0.9355 | 0.8547 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10056.021 | 0.9938 | 0.9860 | 0.8839 |