Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10056.021 | 0.9473 | 0.8811 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10056.021 | 0.9737 | 0.9407 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10056.021 | 0.9295 | 0.8412 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10056.021 | 0.7306 | 0.4022 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10056.021 | 0.1162 | -0.8249 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10056.021 | 0.0333 | -0.9575 | 0.8839 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7854.017 | 0.9234 | 0.8820 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7854.017 | 0.9776 | 0.9657 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7854.017 | 0.9309 | 0.8936 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7854.017 | 0.8398 | 0.7504 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7854.017 | 0.8718 | 0.8011 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7854.017 | 0.4502 | 0.0877 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7854.017 | 0.1365 | -0.5625 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7854.017 | 0.1129 | -0.6216 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7854.017 | 0.0319 | -0.8559 | 1.3102 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9453.017 | 1.0238 | 1.0386 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9453.017 | 1.0350 | 1.0567 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9453.017 | 1.0040 | 1.0066 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9453.017 | 0.9787 | 0.9652 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9453.017 | 1.0079 | 1.0129 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9453.017 | 0.6174 | 0.3504 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9453.017 | 0.2110 | -0.4366 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9453.017 | 0.0460 | -0.8371 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9453.017 | 0.0177 | -0.9253 | 1.2279 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9469.131 | 0.9973 | 0.9949 | 1.0627 |