Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9469.131 | 0.9670 | 0.9379 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9469.131 | 0.9753 | 0.9536 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9469.131 | 0.9993 | 0.9988 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9469.131 | 1.0087 | 1.0163 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9469.131 | 0.7573 | 0.5397 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9469.131 | 0.2408 | -0.4762 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9469.131 | 0.0631 | -0.8514 | 1.0627 | |
| HCC38 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9469.131 | 0.0166 | -0.9577 | 1.0627 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7857.017 | 0.9963 | 0.9938 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7857.017 | 0.9882 | 0.9801 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7857.017 | 0.9885 | 0.9805 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7857.017 | 0.9616 | 0.9349 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7857.017 | 0.9751 | 0.9579 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7857.017 | 0.5673 | 0.2391 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7857.017 | 0.0106 | -0.9571 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7857.017 | 0.0061 | -0.9732 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7857.017 | 0.0062 | -0.9727 | 1.1840 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7860.017 | 1.0564 | 1.1853 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7860.017 | 0.9431 | 0.8196 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7860.017 | 1.0263 | 1.0856 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7860.017 | 0.9963 | 0.9882 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7860.017 | 0.9993 | 0.9978 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7860.017 | 0.9253 | 0.7643 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7860.017 | 0.0279 | -0.9938 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7860.017 | 0.0088 | -0.9990 | 0.6196 |