Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7809.018 | 1.0756 | 1.0889 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7809.018 | 0.9213 | 0.9044 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7809.018 | 0.7807 | 0.7251 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7809.018 | 0.7897 | 0.7369 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7809.018 | 0.7256 | 0.6513 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7809.018 | 0.6231 | 0.5078 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7809.018 | 0.5089 | 0.3360 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7809.018 | 0.5027 | 0.3263 | 1.6742 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7810.006 | 1.0495 | 1.1019 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7810.006 | 0.9871 | 0.9735 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7810.006 | 1.0245 | 1.0503 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7810.006 | 0.7398 | 0.4673 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7810.006 | 0.8389 | 0.6696 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7810.006 | 0.7933 | 0.5764 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7810.006 | 0.7245 | 0.4362 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7810.006 | 0.2190 | -0.5801 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7810.006 | 0.0112 | -0.9802 | 0.9730 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.00128 | uM | 9233.124 | 1.0853 | 1.1709 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0064 | uM | 9233.124 | 0.9973 | 0.9946 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.032 | uM | 9233.124 | 1.0646 | 1.1293 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.16 | uM | 9233.124 | 0.9939 | 0.9879 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.8 | uM | 9233.124 | 0.8995 | 0.7988 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 4 | uM | 9233.124 | 0.8748 | 0.7493 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 20 | uM | 9233.124 | 0.8902 | 0.7801 | 0.9990 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 100 | uM | 9233.124 | 0.7171 | 0.4338 | 0.9990 |