Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9024.018 | 0.6325 | 0.7012 | 2.8306 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9024.018 | 0.5674 | 0.6372 | 2.8306 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9024.018 | 0.2819 | 0.2787 | 2.8306 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9024.018 | 0.0058 | -0.6766 | 2.8306 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10261.026 | 1.0974 | 1.0762 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 10261.026 | 0.9557 | 0.9639 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 10261.026 | 0.6967 | 0.7294 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 10261.026 | 0.5830 | 0.6099 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 10261.026 | 0.5956 | 0.6238 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 10261.026 | 0.5640 | 0.5885 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 10261.026 | 0.5481 | 0.5704 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 10261.026 | 0.1740 | -0.0101 | 2.4866 | ||
| BT-549 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 10261.026 | 0.0058 | -0.7483 | 2.4866 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7805.018 | 1.0795 | 1.1381 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7805.018 | 0.9104 | 0.8426 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7805.018 | 0.7894 | 0.6269 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7805.018 | 0.7370 | 0.5320 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7805.018 | 0.8381 | 0.7141 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7805.018 | 0.7857 | 0.6202 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7805.018 | 0.8065 | 0.6576 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7805.018 | 0.7287 | 0.5170 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7805.018 | 0.0123 | -0.9572 | 1.1451 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9210.026 | 1.0324 | 1.0713 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9210.026 | 0.9667 | 0.9269 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9210.026 | 0.9924 | 0.9833 | 0.9102 |