Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9913.021 | 0.9381 | 0.6576 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9913.021 | 1.0630 | 1.3933 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9913.021 | 0.8942 | 0.4397 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9913.021 | 0.7345 | -0.1928 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9913.021 | 0.1108 | -0.9969 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9913.021 | 0.0385 | -0.9999 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10150.021 | 1.0146 | 1.0602 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10150.021 | 1.0723 | 1.3073 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10150.021 | 1.0931 | 1.4001 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10150.021 | 0.8836 | 0.5523 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10150.021 | 0.9737 | 0.8936 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10150.021 | 0.8983 | 0.6055 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10150.021 | 0.6825 | -0.0852 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10150.021 | 0.2026 | -0.9240 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10150.021 | 0.0386 | -0.9974 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10151.021 | 1.0012 | 1.0077 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10151.021 | 0.9247 | 0.5470 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10151.021 | 1.0444 | 1.3064 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10151.021 | 1.0037 | 1.0244 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10151.021 | 1.0233 | 1.1568 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10151.021 | 0.9607 | 0.7533 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10151.021 | 0.6546 | -0.5020 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10151.021 | 0.1255 | -0.9978 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10151.021 | 0.0358 | -1.0000 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10267.131 | 1.0895 | 1.4989 | 0.3849 |