Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9889.021 | 0.6131 | 0.4107 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9889.021 | 0.2610 | -0.2329 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9889.021 | 0.0770 | -0.6789 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9889.021 | 0.0225 | -0.8666 | 1.4017 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9897.021 | 1.0223 | 1.0734 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9897.021 | 0.9578 | 0.8636 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9897.021 | 1.0657 | 1.2196 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9897.021 | 0.9841 | 0.9483 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9897.021 | 1.0009 | 1.0029 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9897.021 | 0.9179 | 0.7382 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9897.021 | 0.7338 | 0.2043 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9897.021 | 0.4931 | -0.3720 | 0.6103 | |
| T47D | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9897.021 | 0.3221 | -0.6875 | 0.6103 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7926.017 | 1.1424 | 1.3228 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7926.017 | 0.9780 | 0.9506 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7926.017 | 1.1329 | 1.3013 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7926.017 | 0.9980 | 0.9955 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7926.017 | 1.0402 | 1.0906 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7926.017 | 0.8899 | 0.7541 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7926.017 | 0.6996 | 0.3384 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7926.017 | 0.2076 | -0.6584 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7926.017 | 0.0894 | -0.8675 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9913.021 | 1.1444 | 1.9734 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9913.021 | 0.9044 | 0.4885 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9913.021 | 1.1451 | 1.9787 | 0.3401 |