Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7833.05 | 1.1290 | 1.2221 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7833.05 | 0.4866 | 0.0704 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7833.05 | 0.3021 | -0.2922 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7833.05 | 0.2482 | -0.4032 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7833.05 | 0.2165 | -0.4700 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7833.05 | 0.1394 | -0.6382 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7834.05 | 0.9865 | 0.9858 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7834.05 | 0.9462 | 0.9428 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7834.05 | 0.9429 | 0.9391 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7834.05 | 1.0119 | 1.0124 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7834.05 | 0.3206 | 0.0999 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7834.05 | 0.2454 | -0.0443 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7834.05 | 0.2082 | -0.1233 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7834.05 | 0.1718 | -0.2075 | 1.9027 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7834.05 | 0.1043 | -0.3903 | 1.9027 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7836.05 | 0.9809 | 0.9740 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7836.05 | 1.0795 | 1.1062 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7836.05 | 0.9048 | 0.8691 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7836.05 | 0.8938 | 0.8538 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7836.05 | 0.1743 | -0.3862 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7836.05 | 0.1550 | -0.4330 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7836.05 | 0.1413 | -0.4673 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7836.05 | 0.1515 | -0.4418 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7836.05 | 0.0541 | -0.7216 | 1.4789 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7837.05 | 0.8835 | 0.8608 | 1.7172 |