Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7829.04 | 0.1221 | -0.3221 | 1.9437 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7829.04 | 0.1040 | -0.3759 | 1.9437 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7829.04 | 0.1334 | -0.2906 | 1.9437 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7829.04 | 0.0944 | -0.4061 | 1.9437 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9376.037 | 1.0844 | 1.1213 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9376.037 | 1.0542 | 1.0782 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9376.037 | 0.9899 | 0.9852 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9376.037 | 0.9281 | 0.8945 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9376.037 | 0.2632 | -0.2419 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9376.037 | 0.1864 | -0.4101 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 9376.037 | 0.1917 | -0.3978 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 9376.037 | 0.2151 | -0.3453 | 1.3761 | |
| HCC1806 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 9376.037 | 0.0971 | -0.6328 | 1.3761 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7832.04 | 1.0186 | 1.0288 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7832.04 | 1.0802 | 1.1233 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7832.04 | 1.0368 | 1.0568 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7832.04 | 1.0666 | 1.1026 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7832.04 | 0.3419 | -0.1302 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7832.04 | 0.2350 | -0.3499 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7832.04 | 0.2212 | -0.3795 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7832.04 | 0.1787 | -0.4742 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7832.04 | 0.0823 | -0.7120 | 1.2889 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7833.05 | 1.0182 | 1.0315 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7833.05 | 1.0350 | 1.0606 | 1.1523 | |
| HCC1937 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7833.05 | 1.0071 | 1.0124 | 1.1523 |