Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7899.017 | 1.1396 | 1.1323 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7899.017 | 0.9668 | 0.9671 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7899.017 | 1.0371 | 1.0361 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7899.017 | 0.9668 | 0.9671 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7899.017 | 0.7738 | 0.7637 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7899.017 | 0.6376 | 0.6039 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7899.017 | 0.5025 | 0.4272 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7899.017 | 0.3031 | 0.1139 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7900.017 | 0.9632 | 0.8656 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7900.017 | 1.0717 | 1.2747 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7900.017 | 0.5838 | -0.2641 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7900.017 | 1.4990 | 3.2423 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7900.017 | 0.9545 | 0.8342 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7900.017 | 1.0769 | 1.2952 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7900.017 | 1.0095 | 1.0353 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7900.017 | 0.5445 | -0.3533 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7900.017 | 0.3141 | -0.7673 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7902.13 | 0.9220 | 0.9101 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7902.13 | 1.3707 | 1.3909 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7902.13 | 0.8465 | 0.8200 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7902.13 | 1.0781 | 1.0870 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7902.13 | 1.1132 | 1.1252 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7902.13 | 0.8444 | 0.8174 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7902.13 | 0.6358 | 0.5477 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7902.13 | 0.5375 | 0.4072 | 1.7664 |