Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7905.016 | 1.0896 | 1.2950 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7906.016 | 0.8480 | 0.6286 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7906.016 | 0.6778 | 0.2320 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7906.016 | 1.0749 | 1.1884 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7906.016 | 0.7812 | 0.4705 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7906.016 | 1.0255 | 1.0638 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7906.016 | 0.7519 | 0.4021 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7906.016 | 0.8580 | 0.6526 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7906.016 | 0.9051 | 0.7663 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7906.016 | 0.3913 | -0.3786 | 0.8028 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7907.016 | 1.1458 | 1.2182 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7907.016 | 0.8364 | 0.7458 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7907.016 | 1.1445 | 1.2163 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7907.016 | 0.8133 | 0.7091 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7907.016 | 1.1436 | 1.2149 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7907.016 | 1.0179 | 1.0271 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7907.016 | 0.9937 | 0.9905 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7907.016 | 1.1144 | 1.1718 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7907.016 | 0.7929 | 0.6764 | 1.3145 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7909.016 | 1.1899 | 1.2706 | 1.3701 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7909.016 | 0.8917 | 0.8395 | 1.3701 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7909.016 | 1.2713 | 1.3829 | 1.3701 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7909.016 | 0.9996 | 0.9995 | 1.3701 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7909.016 | 1.1578 | 1.2257 | 1.3701 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7909.016 | 1.0139 | 1.0202 | 1.3701 |