Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15292.203 | 0.0521 | -0.7060 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15292.203 | 0.0516 | -0.7075 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15292.203 | 0.0516 | -0.7075 | 1.5415 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7429.074 | 1.0201 | 1.0171 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7429.074 | 1.0201 | 1.0171 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7429.074 | 1.0291 | 1.0247 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7429.074 | 1.0291 | 1.0247 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7429.074 | 1.0048 | 1.0041 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7429.074 | 1.0048 | 1.0041 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7429.074 | 1.0313 | 1.0265 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7429.074 | 1.0313 | 1.0265 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7429.074 | 0.2202 | 0.0469 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7429.074 | 0.2202 | 0.0469 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7429.074 | 0.0089 | -0.7341 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7429.074 | 0.0089 | -0.7341 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7429.074 | 0.0030 | -0.8326 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7429.074 | 0.0030 | -0.8326 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7429.074 | 0.0119 | -0.7001 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7429.074 | 0.0119 | -0.7001 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7429.074 | 0.0049 | -0.7951 | 2.3375 | |
| HBL-100 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7429.074 | 0.0049 | -0.7951 | 2.3375 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7430.074 | 1.0422 | 1.0494 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7430.074 | 1.0422 | 1.0494 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7430.074 | 1.0455 | 1.0533 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7430.074 | 1.0455 | 1.0533 | 1.6943 |