Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7430.074 | 1.0099 | 1.0116 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7430.074 | 1.0099 | 1.0116 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7430.074 | 0.3645 | 0.1024 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7430.074 | 0.3645 | 0.1024 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7430.074 | 0.0999 | -0.4866 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7430.074 | 0.0999 | -0.4866 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7430.074 | 0.0442 | -0.6827 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7430.074 | 0.0442 | -0.6827 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7430.074 | 0.0188 | -0.8082 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7430.074 | 0.0188 | -0.8082 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7430.074 | 0.0160 | -0.8261 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7430.074 | 0.0160 | -0.8261 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7430.074 | 0.0229 | -0.7845 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7430.074 | 0.0229 | -0.7845 | 1.6943 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14829.203 | 0.9559 | 0.9304 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14829.203 | 0.9559 | 0.9304 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14829.203 | 0.8921 | 0.8286 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14829.203 | 0.8921 | 0.8286 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14829.203 | 0.6549 | 0.4347 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14829.203 | 0.6549 | 0.4347 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14829.203 | 0.3323 | -0.1576 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14829.203 | 0.3323 | -0.1576 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14829.203 | 0.0843 | -0.7129 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14829.203 | 0.0843 | -0.7129 | 1.2743 | |
| HCC1143 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14829.203 | 0.0460 | -0.8217 | 1.2743 |