Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5909.074 | 0.0409 | -0.3462 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5909.074 | 0.0409 | -0.3462 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5909.074 | 0.0019 | -0.7754 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5909.074 | 0.0019 | -0.7754 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5909.074 | 0.0005 | -0.8617 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5909.074 | 0.0005 | -0.8617 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5909.074 | 0.0004 | -0.8749 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5909.074 | 0.0004 | -0.8749 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5909.074 | 0.0030 | -0.7375 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5909.074 | 0.0030 | -0.7375 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 5909.074 | 0.0006 | -0.8505 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 5909.074 | 0.0006 | -0.8505 | 2.8598 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5910.074 | 0.9723 | 0.9826 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5910.074 | 0.9723 | 0.9826 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5910.074 | 1.0000 | 1.0000 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5910.074 | 1.0000 | 1.0000 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5910.074 | 0.9679 | 0.9798 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5910.074 | 0.9679 | 0.9798 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5910.074 | 0.0395 | -0.2673 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5910.074 | 0.0395 | -0.2673 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 |