Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14715.203 | 0.0241 | -0.6846 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14715.203 | 0.0241 | -0.6846 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14715.203 | 0.0132 | -0.7658 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14715.203 | 0.0132 | -0.7658 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14715.203 | 0.0100 | -0.7958 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14715.203 | 0.0100 | -0.7958 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14715.203 | 0.0143 | -0.7562 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14715.203 | 0.0143 | -0.7562 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14715.203 | 0.0120 | -0.7771 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14715.203 | 0.0120 | -0.7771 | 2.0168 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5898.074 | 0.9804 | 0.9451 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5898.074 | 0.9804 | 0.9451 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5898.074 | 0.9334 | 0.8158 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5898.074 | 0.9334 | 0.8158 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5898.074 | 1.0227 | 1.0640 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5898.074 | 1.0227 | 1.0640 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5898.074 | 0.9845 | 0.9568 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5898.074 | 0.9845 | 0.9568 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5898.074 | 0.9735 | 0.9262 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5898.074 | 0.9735 | 0.9262 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5898.074 | 0.8269 | 0.5323 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5898.074 | 0.8269 | 0.5323 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5898.074 | 0.6348 | 0.0578 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5898.074 | 0.6348 | 0.0578 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5898.074 | 0.2926 | -0.6429 | 0.7134 |