Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14924.203 | 0.0533 | -0.8926 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14924.203 | 0.0533 | -0.8926 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14924.203 | 0.0163 | -0.9672 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14924.203 | 0.0163 | -0.9672 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14924.203 | 0.0154 | -0.9690 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14924.203 | 0.0154 | -0.9690 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14924.203 | 0.0131 | -0.9735 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14924.203 | 0.0131 | -0.9735 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14924.203 | 0.0227 | -0.9541 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14924.203 | 0.0227 | -0.9541 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14924.203 | 0.0214 | -0.9568 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14924.203 | 0.0214 | -0.9568 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15340.203 | 1.0033 | 1.0046 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15340.203 | 1.0033 | 1.0046 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15340.203 | 0.9842 | 0.9781 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15340.203 | 0.9842 | 0.9781 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15340.203 | 0.5942 | 0.3949 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15340.203 | 0.5942 | 0.3949 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15340.203 | 0.0540 | -0.7348 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15340.203 | 0.0540 | -0.7348 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15340.203 | 0.0126 | -0.9030 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15340.203 | 0.0126 | -0.9030 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15340.203 | 0.0111 | -0.9110 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15340.203 | 0.0111 | -0.9110 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15340.203 | 0.0069 | -0.9359 | 1.4449 |