Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7542.074 | 0.0081 | -0.9251 | 1.4673 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7543.074 | 0.9867 | 0.9790 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7543.074 | 0.9867 | 0.9790 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7543.074 | 0.9841 | 0.9748 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7543.074 | 0.9841 | 0.9748 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7543.074 | 0.9872 | 0.9797 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7543.074 | 0.9872 | 0.9797 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7543.074 | 0.4380 | 0.0410 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7543.074 | 0.4380 | 0.0410 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7543.074 | 0.0005 | -0.9954 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7543.074 | 0.0034 | -0.9779 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7543.074 | 0.0034 | -0.9779 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7543.074 | 0.0021 | -0.9846 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7543.074 | 0.0021 | -0.9846 | 1.2642 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14924.203 | 0.9738 | 0.9477 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14924.203 | 0.9738 | 0.9477 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14924.203 | 0.9758 | 0.9518 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14924.203 | 0.9758 | 0.9518 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14924.203 | 0.7242 | 0.4494 | 1.0024 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14924.203 | 0.7242 | 0.4494 | 1.0024 |