Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15340.203 | 0.0069 | -0.9359 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15340.203 | 0.0121 | -0.9060 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15340.203 | 0.0121 | -0.9060 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15340.203 | 0.0114 | -0.9095 | 1.4449 | |
| T47D | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15340.203 | 0.0114 | -0.9095 | 1.4449 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7546.074 | 1.0064 | 1.0151 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7546.074 | 1.0064 | 1.0151 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7546.074 | 1.0387 | 1.0919 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7546.074 | 1.0387 | 1.0919 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7546.074 | 1.0244 | 1.0577 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7546.074 | 1.0244 | 1.0577 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7546.074 | 1.0733 | 1.1743 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7546.074 | 1.0733 | 1.1743 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7546.074 | 0.9988 | 0.9972 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7546.074 | 0.9988 | 0.9972 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7546.074 | 0.7630 | 0.4530 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7546.074 | 0.7630 | 0.4530 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7546.074 | 0.4145 | -0.2933 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7546.074 | 0.4145 | -0.2933 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7546.074 | 0.0708 | -0.9124 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7546.074 | 0.0708 | -0.9124 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7546.074 | 0.0281 | -0.9706 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7546.074 | 0.0281 | -0.9706 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14849.203 | 1.0200 | 1.0503 | 0.7976 | |
| T47DKBLUC | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14849.203 | 1.0200 | 1.0503 | 0.7976 |