Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5898.074 | 0.2926 | -0.6429 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5898.074 | 0.1259 | -0.8905 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5898.074 | 0.1259 | -0.8905 | 0.7134 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5899.074 | 0.9576 | 0.9045 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5899.074 | 0.9576 | 0.9045 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5899.074 | 0.9646 | 0.9203 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5899.074 | 0.9646 | 0.9203 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5899.074 | 0.9559 | 0.9006 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5899.074 | 0.9559 | 0.9006 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5899.074 | 1.0045 | 1.0102 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5899.074 | 1.0045 | 1.0102 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5899.074 | 0.5690 | 0.0584 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5899.074 | 0.5690 | 0.0584 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5899.074 | 0.0784 | -0.8870 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5899.074 | 0.0784 | -0.8870 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5899.074 | 0.0147 | -0.9829 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5899.074 | 0.0147 | -0.9829 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5899.074 | 0.0197 | -0.9762 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5899.074 | 0.0197 | -0.9762 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5899.074 | 0.0132 | -0.9849 | 0.8860 | |
| 600MPE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5899.074 | 0.0132 | -0.9849 | 0.8860 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5900.074 | 0.9710 | 0.9758 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5900.074 | 0.9710 | 0.9758 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5900.074 | 1.0225 | 1.0185 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5900.074 | 1.0225 | 1.0185 | 2.4189 |