Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10695.072 | 0.3720 | -0.2003 | 1.0788 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7542.072 | 1.0546 | 1.0828 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7542.072 | 1.0045 | 1.0068 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7542.072 | 1.0461 | 1.0700 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7542.072 | 1.0388 | 1.0589 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7542.072 | 1.0262 | 1.0399 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7542.072 | 0.9879 | 0.9815 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7542.072 | 1.0272 | 1.0414 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7542.072 | 0.5319 | 0.2352 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7542.072 | 0.3239 | -0.1542 | 1.3099 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10939.072 | 0.9817 | 0.9779 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10939.072 | 0.9575 | 0.9485 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10939.072 | 1.0207 | 1.0247 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10939.072 | 1.0412 | 1.0490 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10939.072 | 0.9450 | 0.9333 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10939.072 | 1.0254 | 1.0303 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10939.072 | 0.9116 | 0.8919 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10939.072 | 0.7165 | 0.6374 | 1.6668 | |
| T47D | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10939.072 | 0.2134 | -0.2083 | 1.6668 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7544.072 | 1.0184 | 1.0328 | 1.1203 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7544.072 | 0.9131 | 0.8442 | 1.1203 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7544.072 | 0.9510 | 0.9123 | 1.1203 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7544.072 | 0.9302 | 0.8749 | 1.1203 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7544.072 | 0.9485 | 0.9077 | 1.1203 | |
| T47DKBLUC | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7544.072 | 0.9148 | 0.8472 | 1.1203 |