Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 11058.072 | 0.8501 | 0.8638 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 11058.072 | 0.9223 | 0.9310 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 11058.072 | 0.8720 | 0.8845 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 11058.072 | 0.8943 | 0.9053 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 11058.072 | 0.8869 | 0.8984 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 11058.072 | 0.8439 | 0.8579 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 11058.072 | 0.8122 | 0.8272 | 2.3023 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 11058.072 | 0.7222 | 0.7363 | 2.3023 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7539.072 | 0.9736 | 0.9642 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7539.072 | 0.8719 | 0.8231 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7539.072 | 0.9327 | 0.9081 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7539.072 | 1.0042 | 1.0057 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7539.072 | 0.9855 | 0.9804 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7539.072 | 0.9236 | 0.8954 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7539.072 | 0.9884 | 0.9844 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7539.072 | 0.8504 | 0.7925 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7539.072 | 0.5599 | 0.3516 | 1.4799 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10695.072 | 1.1153 | 1.2129 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10695.072 | 0.9989 | 0.9979 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10695.072 | 1.0101 | 1.0187 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10695.072 | 1.0420 | 1.0777 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10695.072 | 1.1104 | 1.2038 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10695.072 | 0.9670 | 0.9387 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10695.072 | 1.0811 | 1.1499 | 1.0788 | |
| SUM52PE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10695.072 | 0.7843 | 0.5967 | 1.0788 |