Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5900.074 | 0.9430 | 0.9520 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5900.074 | 0.9430 | 0.9520 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5900.074 | 0.0599 | -0.3753 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5900.074 | 0.0599 | -0.3753 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5900.074 | 0.0091 | -0.7130 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5900.074 | 0.0091 | -0.7130 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5900.074 | 0.0044 | -0.7878 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5900.074 | 0.0044 | -0.7878 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5900.074 | 0.0034 | -0.8092 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5900.074 | 0.0034 | -0.8092 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5900.074 | 0.0071 | -0.7420 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5900.074 | 0.0071 | -0.7420 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5900.074 | 0.0078 | -0.7311 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5900.074 | 0.0078 | -0.7311 | 2.4189 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5901.074 | 0.9843 | 0.9832 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5901.074 | 0.9843 | 0.9832 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5901.074 | 1.0067 | 1.0071 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5901.074 | 1.0067 | 1.0071 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5901.074 | 0.9161 | 0.9085 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5901.074 | 0.9161 | 0.9085 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5901.074 | 0.0179 | -0.7667 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5901.074 | 0.0179 | -0.7667 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5901.074 | 0.0040 | -0.8948 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5901.074 | 0.0040 | -0.8948 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5901.074 | 0.0002 | -0.9772 | 1.8718 |