Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5901.074 | 0.0002 | -0.9772 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5901.074 | 0.0008 | -0.9566 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5901.074 | 0.0008 | -0.9566 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5901.074 | 0.0017 | -0.9339 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5901.074 | 0.0017 | -0.9339 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5901.074 | 0.0032 | -0.9066 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5901.074 | 0.0032 | -0.9066 | 1.8718 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14817.203 | 0.9800 | 0.9740 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14817.203 | 0.9800 | 0.9740 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14817.203 | 0.9732 | 0.9651 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14817.203 | 0.9732 | 0.9651 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14817.203 | 0.4219 | 0.1438 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14817.203 | 0.4219 | 0.1438 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14817.203 | 0.0459 | -0.7281 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14817.203 | 0.0459 | -0.7281 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14817.203 | 0.0234 | -0.8243 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14817.203 | 0.0234 | -0.8243 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14817.203 | 0.0164 | -0.8604 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14817.203 | 0.0164 | -0.8604 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14817.203 | 0.0121 | -0.8852 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14817.203 | 0.0121 | -0.8852 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14817.203 | 0.0200 | -0.8411 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14817.203 | 0.0200 | -0.8411 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14817.203 | 0.0244 | -0.8194 | 1.5445 | |
| AU565 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14817.203 | 0.0244 | -0.8194 | 1.5445 |