Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10420.072 | 0.9853 | 0.9417 | 0.5007 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10420.072 | 0.9215 | 0.6987 | 0.5007 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10420.072 | 0.9962 | 0.9848 | 0.5007 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10420.072 | 0.9374 | 0.7579 | 0.5007 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10420.072 | 0.8920 | 0.5919 | 0.5007 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10580.072 | 0.9836 | 0.9621 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10580.072 | 0.9444 | 0.8718 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10580.072 | 0.9230 | 0.8225 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10580.072 | 0.9549 | 0.8959 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10580.072 | 0.9447 | 0.8723 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10580.072 | 0.9354 | 0.8509 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10580.072 | 0.9534 | 0.8923 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10580.072 | 0.9197 | 0.8152 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10580.072 | 0.6194 | 0.1478 | 0.8627 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10754.072 | 0.9621 | 0.9429 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10754.072 | 0.9324 | 0.8977 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10754.072 | 0.9767 | 0.9650 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10754.072 | 0.9604 | 0.9403 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10754.072 | 0.9854 | 0.9780 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10754.072 | 0.9229 | 0.8832 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10754.072 | 1.0039 | 1.0058 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10754.072 | 0.8665 | 0.7962 | 1.3338 | |
| UACC-812 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10754.072 | 0.0013 | -0.9864 | 1.3338 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7553.073 | 1.0111 | 1.0188 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7553.073 | 0.9515 | 0.9173 | 1.1779 |