Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7553.073 | 0.9910 | 0.9848 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7553.073 | 0.9984 | 0.9973 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7553.073 | 0.9835 | 0.9719 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7553.073 | 0.9524 | 0.9189 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7553.073 | 1.0149 | 1.0252 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7553.073 | 0.9491 | 0.9133 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7553.073 | 0.7930 | 0.6425 | 1.1779 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10444.072 | 1.0144 | 1.0324 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10444.072 | 0.9319 | 0.8477 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10444.072 | 0.9924 | 0.9829 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10444.072 | 0.9877 | 0.9725 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10444.072 | 1.0155 | 1.0349 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10444.072 | 0.9556 | 0.9005 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10444.072 | 1.0090 | 1.0201 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10444.072 | 0.9084 | 0.7954 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10444.072 | 0.6390 | 0.2094 | 0.8902 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 11660.072 | 0.9499 | 0.8943 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 11660.072 | 0.9008 | 0.7913 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 11660.072 | 0.9134 | 0.8176 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 11660.072 | 0.9407 | 0.8750 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 11660.072 | 0.9421 | 0.8779 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 11660.072 | 0.8611 | 0.7081 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 11660.072 | 0.9443 | 0.8826 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 11660.072 | 0.8370 | 0.6576 | 0.9478 | |
| ZR-75-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 11660.072 | 0.5823 | 0.1304 | 0.9478 |