Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14853.203 | 0.4713 | -0.2432 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14853.203 | 0.4811 | -0.2228 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14853.203 | 0.4811 | -0.2228 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14853.203 | 0.2501 | -0.6663 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14853.203 | 0.2501 | -0.6663 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14853.203 | 0.1896 | -0.7667 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14853.203 | 0.1896 | -0.7667 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14853.203 | 0.2266 | -0.7062 | 0.7740 | |
| UACC-812 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14853.203 | 0.2266 | -0.7062 | 0.7740 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7552.074 | 1.0202 | 1.0440 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7552.074 | 1.0202 | 1.0440 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7552.074 | 1.0155 | 1.0338 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7552.074 | 1.0155 | 1.0338 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7552.074 | 1.0396 | 1.0864 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7552.074 | 1.0396 | 1.0864 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7552.074 | 0.9645 | 0.9226 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7552.074 | 0.9645 | 0.9226 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7552.074 | 0.5397 | 0.0210 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7552.074 | 0.5397 | 0.0210 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7552.074 | 0.4157 | -0.2318 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7552.074 | 0.4157 | -0.2318 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7552.074 | 0.2672 | -0.5255 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7552.074 | 0.2672 | -0.5255 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7552.074 | 0.1447 | -0.7569 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7552.074 | 0.1447 | -0.7569 | 0.9174 |