Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7552.074 | 0.1265 | -0.7900 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7552.074 | 0.1265 | -0.7900 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7553.074 | 1.0197 | 1.0415 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7553.074 | 1.0197 | 1.0415 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7553.074 | 0.9238 | 0.8402 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7553.074 | 0.9238 | 0.8402 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7553.074 | 0.9933 | 0.9859 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7553.074 | 0.9933 | 0.9859 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7553.074 | 0.9421 | 0.8784 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7553.074 | 0.9421 | 0.8784 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7553.074 | 0.4827 | -0.0698 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7553.074 | 0.4827 | -0.0698 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7553.074 | 0.3347 | -0.3669 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7553.074 | 0.3347 | -0.3669 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7553.074 | 0.2500 | -0.5342 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7553.074 | 0.2500 | -0.5342 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7553.074 | 0.1592 | -0.7101 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7553.074 | 0.1592 | -0.7101 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7553.074 | 0.1415 | -0.7439 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7553.074 | 0.1415 | -0.7439 | 0.9515 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14927.203 | 0.9759 | 0.9457 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14927.203 | 0.9759 | 0.9457 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14927.203 | 0.9871 | 0.9710 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14927.203 | 0.9871 | 0.9710 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14927.203 | 0.9962 | 0.9914 | 0.8860 |