Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14927.203 | 0.9962 | 0.9914 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14927.203 | 0.5602 | 0.0399 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14927.203 | 0.5602 | 0.0399 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14927.203 | 0.4353 | -0.2178 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14927.203 | 0.4353 | -0.2178 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14927.203 | 0.3388 | -0.4106 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14927.203 | 0.3388 | -0.4106 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14927.203 | 0.1371 | -0.7876 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14927.203 | 0.1371 | -0.7876 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14927.203 | 0.0729 | -0.8960 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14927.203 | 0.0729 | -0.8960 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14927.203 | 0.0847 | -0.8768 | 0.8860 | |
| ZR-75-1 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14927.203 | 0.0847 | -0.8768 | 0.8860 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7555.074 | 0.9109 | 0.8911 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7555.074 | 0.9109 | 0.8911 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7555.074 | 0.8978 | 0.8749 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7555.074 | 0.8978 | 0.8749 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7555.074 | 1.0217 | 1.0259 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7555.074 | 1.0217 | 1.0259 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7555.074 | 0.8535 | 0.8188 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7555.074 | 0.8535 | 0.8188 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7555.074 | 0.4636 | 0.2615 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7555.074 | 0.4636 | 0.2615 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7555.074 | 0.3024 | -0.0235 | 1.6682 | |
| ZR75B | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7555.074 | 0.3024 | -0.0235 | 1.6682 |