Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7537.074 | 0.2369 | -0.0237 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7537.074 | 0.0371 | -0.6123 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7537.074 | 0.0371 | -0.6123 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7537.074 | 0.0179 | -0.7306 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7537.074 | 0.0179 | -0.7306 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7537.074 | 0.0099 | -0.7991 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7537.074 | 0.0099 | -0.7991 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7537.074 | 0.0115 | -0.7839 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7537.074 | 0.0115 | -0.7839 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 167 | uM | 7537.074 | 0.0130 | -0.7702 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 167 | uM | 7537.074 | 0.0130 | -0.7702 | 2.0080 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14807.203 | 1.0191 | 1.0222 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14807.203 | 1.0191 | 1.0222 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14807.203 | 0.9450 | 0.9351 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14807.203 | 0.9450 | 0.9351 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14807.203 | 0.5212 | 0.3677 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14807.203 | 0.5212 | 0.3677 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14807.203 | 0.0471 | -0.6634 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14807.203 | 0.0471 | -0.6634 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14807.203 | 0.0672 | -0.5857 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14807.203 | 0.0672 | -0.5857 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14807.203 | 0.0478 | -0.6602 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14807.203 | 0.0478 | -0.6602 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14807.203 | 0.0179 | -0.8087 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14807.203 | 0.0179 | -0.8087 | 1.7148 |