Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7821.042 | 0.9800 | 0.9282 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7821.042 | 0.9228 | 0.7291 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7821.042 | 0.9842 | 0.9430 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7821.042 | 0.9506 | 0.8247 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7821.042 | 1.0600 | 1.2224 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7821.042 | 0.9389 | 0.7843 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9278.026 | 0.9314 | 0.6223 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9278.026 | 1.0337 | 1.2048 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9278.026 | 0.9771 | 0.8679 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9278.026 | 0.9704 | 0.8306 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9278.026 | 1.0163 | 1.0974 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9278.026 | 0.9967 | 0.9806 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9278.026 | 0.9918 | 0.9519 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9278.026 | 1.0197 | 1.1183 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9278.026 | 0.9767 | 0.8659 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10019.124 | 1.0767 | 1.2958 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10019.124 | 1.0256 | 1.0965 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10019.124 | 1.0299 | 1.1133 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10019.124 | 1.1029 | 1.4014 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10019.124 | 1.0455 | 1.1734 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10019.124 | 1.0913 | 1.3543 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10019.124 | 1.0309 | 1.1170 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 10019.124 | 1.0362 | 1.1372 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 10019.124 | 0.9949 | 0.9810 | 0.5356 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7441.102 | 1.0118 | 1.0257 | 0.9144 |