Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9258.026 | 0.9979 | 0.9926 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9258.026 | 0.9834 | 0.9413 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 9258.026 | 0.9809 | 0.9327 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 9258.026 | 0.9410 | 0.7953 | 0.5632 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7818.018 | 0.9410 | 0.8812 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7818.018 | 0.9348 | 0.8688 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7818.018 | 0.9406 | 0.8804 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7818.018 | 0.9431 | 0.8853 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7818.018 | 0.9160 | 0.8309 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7818.018 | 0.9639 | 0.9274 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7818.018 | 0.9528 | 0.9049 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7818.018 | 1.0141 | 1.0284 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7818.018 | 0.9109 | 0.8205 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7820.042 | 1.0336 | 1.1308 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7820.042 | 1.0613 | 1.2415 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7820.042 | 1.0289 | 1.1124 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7820.042 | 1.0563 | 1.2215 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7820.042 | 1.0591 | 1.2328 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7820.042 | 1.0829 | 1.3301 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7820.042 | 1.0466 | 1.1824 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7820.042 | 1.0533 | 1.2094 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7820.042 | 1.0057 | 1.0221 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7821.042 | 0.9370 | 0.7777 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7821.042 | 0.9726 | 0.9017 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7821.042 | 0.9686 | 0.8879 | 0.5522 |