Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7793.018 | 1.0227 | 1.0344 | 1.3186 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7793.018 | 0.9553 | 0.9318 | 1.3186 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7794.018 | 1.4132 | 1.4568 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7794.018 | 1.4026 | 1.4458 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7794.018 | 1.4493 | 1.4939 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7794.018 | 1.4397 | 1.4841 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7794.018 | 1.5124 | 1.5580 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7794.018 | 1.4272 | 1.4713 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7794.018 | 1.4325 | 1.4767 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7794.018 | 1.4160 | 1.4598 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7794.018 | 1.2711 | 1.3067 | 1.6812 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9035.018 | 1.0285 | 1.0263 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9035.018 | 0.9639 | 0.9662 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9035.018 | 0.9559 | 0.9586 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9035.018 | 1.0664 | 1.0606 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9035.018 | 0.9318 | 0.9355 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9035.018 | 0.9995 | 0.9995 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9035.018 | 0.9688 | 0.9708 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9035.018 | 0.9038 | 0.9083 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9035.018 | 0.9155 | 0.9198 | 2.1555 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9146.122 | 1.0623 | 1.0922 | 1.3408 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9146.122 | 1.0961 | 1.1417 | 1.3408 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9146.122 | 1.0252 | 1.0375 | 1.3408 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9146.122 | 1.1226 | 1.1802 | 1.3408 | |
AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9146.122 | 1.0558 | 1.0827 | 1.3408 |