Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10151.021 | 1.0130 | 1.0868 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10151.021 | 1.0571 | 1.4000 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10151.021 | 1.0645 | 1.4553 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10151.021 | 0.9979 | 0.9863 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10151.021 | 1.0666 | 1.4712 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10151.021 | 0.8651 | 0.2434 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10151.021 | 0.5926 | -0.6408 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10151.021 | 0.0891 | -0.9993 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10151.021 | 0.0745 | -0.9996 | 0.3048 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10267.011 | 1.0921 | 1.5557 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10267.011 | 1.1846 | 2.2054 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10267.011 | 1.0459 | 1.2661 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10267.011 | 1.1416 | 1.8920 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10267.011 | 1.1008 | 1.6129 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10267.011 | 0.9616 | 0.7934 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10267.011 | 0.5788 | -0.5637 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10267.011 | 0.0756 | -0.9985 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10267.011 | 0.1104 | -0.9957 | 0.3592 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9045.075 | 1.0669 | 1.1635 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9045.075 | 1.1884 | 1.4664 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9045.075 | 0.9229 | 0.8143 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9045.075 | 1.0922 | 1.2260 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9045.075 | 1.1387 | 1.3417 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9045.075 | 1.0820 | 1.2009 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9045.075 | 1.0796 | 1.1951 | 0.8235 |