Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7791.018 | 1.0127 | 1.0298 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7791.018 | 1.0554 | 1.1301 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7791.018 | 1.0103 | 1.0241 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7791.018 | 1.0373 | 1.0875 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7791.018 | 1.0204 | 1.0478 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7791.018 | 1.0359 | 1.0840 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7791.018 | 1.0322 | 1.0755 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7791.018 | 1.0876 | 1.2063 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7791.018 | 0.9388 | 0.8577 | 0.8558 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9118.006 | 0.9876 | 0.9776 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9118.006 | 1.0030 | 1.0053 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9118.006 | 0.9813 | 0.9663 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9118.006 | 1.0339 | 1.0611 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9118.006 | 0.7945 | 0.6252 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9118.006 | 1.0155 | 1.0280 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9118.006 | 0.9567 | 0.9218 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9118.006 | 0.9389 | 0.8894 | 1.1089 | |
| 600MPE | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9118.006 | 0.9197 | 0.8545 | 1.1089 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7793.018 | 0.9920 | 0.9878 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7793.018 | 0.9841 | 0.9758 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7793.018 | 1.0314 | 1.0474 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7793.018 | 1.0004 | 1.0007 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7793.018 | 1.0003 | 1.0005 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7793.018 | 0.9807 | 0.9707 | 1.3186 | |
| AU565 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7793.018 | 0.9717 | 0.9570 | 1.3186 |