Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7441.102 | 1.0619 | 1.1358 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7441.102 | 0.9950 | 0.9890 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7441.102 | 0.9860 | 0.9694 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7441.102 | 0.9854 | 0.9681 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7441.102 | 0.9443 | 0.8785 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7441.102 | 0.9859 | 0.9692 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7441.102 | 0.9891 | 0.9761 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7441.102 | 1.1283 | 1.2823 | 0.9144 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9294.125 | 1.0092 | 1.0262 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9294.125 | 0.9511 | 0.8618 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9294.125 | 0.9620 | 0.8924 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9294.125 | 0.9955 | 0.9872 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9294.125 | 0.9639 | 0.8977 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9294.125 | 0.9748 | 0.9284 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9294.125 | 1.0120 | 1.0345 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9294.125 | 0.9886 | 0.9676 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9294.125 | 0.9582 | 0.8816 | 0.6999 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7447.102 | 0.9549 | 0.9448 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7447.102 | 0.9794 | 0.9748 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7447.102 | 0.9738 | 0.9680 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7447.102 | 0.9918 | 0.9901 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7447.102 | 0.9712 | 0.9648 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7447.102 | 0.9544 | 0.9441 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7447.102 | 0.9460 | 0.9338 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7447.102 | 0.9683 | 0.9613 | 1.6467 |