Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7447.102 | 0.9706 | 0.9641 | 1.6467 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7824.018 | 1.1996 | 1.2978 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7824.018 | 1.1632 | 1.2443 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7824.018 | 1.0977 | 1.1474 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7824.018 | 1.2132 | 1.3175 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7824.018 | 1.1895 | 1.2830 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7824.018 | 1.1263 | 1.1899 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7824.018 | 1.2663 | 1.3945 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7824.018 | 1.1990 | 1.2968 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7824.018 | 1.1199 | 1.1804 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7825.018 | 0.9380 | 0.9362 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7825.018 | 0.9604 | 0.9595 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7825.018 | 0.9297 | 0.9275 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7825.018 | 1.0347 | 1.0349 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7825.018 | 0.9424 | 0.9408 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7825.018 | 0.9413 | 0.9397 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7825.018 | 0.9837 | 0.9834 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7825.018 | 0.8812 | 0.8759 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7825.018 | 0.8768 | 0.8711 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9347.026 | 1.0302 | 1.0465 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9347.026 | 1.1178 | 1.1793 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9347.026 | 1.0160 | 1.0247 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9347.026 | 1.0772 | 1.1181 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9347.026 | 1.0625 | 1.0958 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9347.026 | 1.0681 | 1.1043 | 1.2965 |