Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9347.026 | 1.0193 | 1.0296 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 9347.026 | 1.0840 | 1.1284 | 1.2965 | |
| HCC1569 | HER2amp | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 9347.026 | 1.0338 | 1.0519 | 1.2965 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7829.042 | 0.9687 | 0.9662 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7829.042 | 0.9887 | 0.9879 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7829.042 | 1.0081 | 1.0086 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7829.042 | 0.9879 | 0.9870 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7829.042 | 1.0335 | 1.0356 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7829.042 | 0.8169 | 0.7947 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7829.042 | 0.7876 | 0.7600 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7829.042 | 0.7930 | 0.7664 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7829.042 | 0.7195 | 0.6767 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7830.018 | 1.1600 | 1.2034 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7830.018 | 1.3114 | 1.3872 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7830.018 | 1.1437 | 1.1832 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7830.018 | 1.3606 | 1.4452 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7830.018 | 1.1997 | 1.2524 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7830.018 | 1.0626 | 1.0809 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7830.018 | 1.0704 | 1.0909 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7830.018 | 1.0266 | 1.0346 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7830.018 | 0.8828 | 0.8437 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9376.026 | 1.0429 | 1.0505 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9376.026 | 1.1041 | 1.1213 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9376.026 | 1.0345 | 1.0407 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9376.026 | 1.0949 | 1.1107 | 1.6827 |