Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7902.13 | 0.3166 | 0.0429 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 10266.131 | 0.9842 | 0.9630 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 10266.131 | 1.1222 | 1.2886 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 10266.131 | 0.9286 | 0.8341 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 10266.131 | 1.0275 | 1.0645 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 10266.131 | 0.9745 | 0.9404 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 10266.131 | 0.8652 | 0.6886 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 10266.131 | 0.7488 | 0.4261 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 10266.131 | 0.6617 | 0.2341 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 10266.131 | 0.4374 | -0.2395 | 0.8552 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7903.017 | 1.0032 | 1.0055 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7903.017 | 1.0258 | 1.0443 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7903.017 | 0.9577 | 0.9270 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7903.017 | 0.8645 | 0.7645 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7903.017 | 0.8032 | 0.6564 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7903.017 | 0.7019 | 0.4750 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7903.017 | 0.5621 | 0.2184 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7903.017 | 0.3465 | -0.1964 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7903.017 | 0.2366 | -0.4212 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9708.017 | 0.9936 | 0.9883 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9708.017 | 0.9904 | 0.9824 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9708.017 | 0.8617 | 0.7459 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9708.017 | 0.8255 | 0.6787 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9708.017 | 0.8280 | 0.6832 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9708.017 | 0.7095 | 0.4619 | 1.0949 |