Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7837.05 | 1.0546 | 1.0629 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7837.05 | 0.8608 | 0.8329 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7837.05 | 0.6809 | 0.5989 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7837.05 | 0.2170 | -0.1785 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7837.05 | 0.2325 | -0.1447 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7837.05 | 0.2103 | -0.1933 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7837.05 | 0.2244 | -0.1623 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7837.05 | 0.0671 | -0.5852 | 1.7172 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7839.05 | 0.9739 | 0.9699 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7839.05 | 1.0638 | 1.0721 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7839.05 | 0.9180 | 0.9044 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7839.05 | 0.6092 | 0.5060 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7839.05 | 0.3333 | 0.0664 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7839.05 | 0.3529 | 0.1017 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7839.05 | 0.3209 | 0.0434 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7839.05 | 0.2457 | -0.1044 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7839.05 | 0.1207 | -0.4040 | 1.7470 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9386.037 | 0.9492 | 0.9245 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9386.037 | 1.1103 | 1.1605 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9386.037 | 1.0669 | 1.0979 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9386.037 | 0.5924 | 0.3593 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9386.037 | 0.2535 | -0.2733 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9386.037 | 0.2594 | -0.2610 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 9386.037 | 0.2373 | -0.3079 | 1.3556 | |
| HCC1954 | HER2amp | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 9386.037 | 0.2040 | -0.3808 | 1.3556 |