Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10266.011 | 0.9778 | 0.9360 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10266.011 | 1.0317 | 1.0927 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10266.011 | 1.0874 | 1.2584 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10266.011 | 0.9831 | 0.9512 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10266.011 | 0.7257 | 0.2564 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10266.011 | 0.3014 | -0.6488 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10266.011 | 0.0823 | -0.9465 | 0.6895 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7903.011 | 0.9807 | 0.9666 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7903.011 | 0.9334 | 0.8840 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7903.011 | 0.9794 | 0.9643 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7903.011 | 0.9863 | 0.9762 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7903.011 | 1.0162 | 1.0281 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7903.011 | 0.9862 | 0.9761 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7903.011 | 0.6740 | 0.4207 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7903.011 | 0.1573 | -0.5976 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7903.011 | 0.0410 | -0.8746 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9708.011 | 1.0165 | 1.0312 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9708.011 | 1.1589 | 1.3006 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9708.011 | 0.9709 | 0.9448 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9708.011 | 1.1012 | 1.1917 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9708.011 | 1.1551 | 1.2933 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9708.011 | 1.0205 | 1.0389 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9708.011 | 0.7637 | 0.5484 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9708.011 | 0.2001 | -0.5658 | 1.0535 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9708.011 | 0.1484 | -0.6731 | 1.0535 |