Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9723.12 | 1.1050 | 1.2513 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9723.12 | 1.1882 | 1.4536 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9723.12 | 1.1007 | 1.2409 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9723.12 | 1.1507 | 1.3620 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9723.12 | 1.1356 | 1.3253 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9723.12 | 1.0508 | 1.1209 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9723.12 | 0.8004 | 0.5360 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9723.12 | 0.2517 | -0.6101 | 0.8437 | |
| MDA-MB-453 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9723.12 | 0.0840 | -0.8939 | 0.8437 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7905.011 | 0.8749 | 0.7258 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7905.011 | 0.9354 | 0.8580 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7905.011 | 0.8415 | 0.6533 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7905.011 | 0.9997 | 0.9992 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7905.011 | 1.0402 | 1.0889 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7905.011 | 0.9588 | 0.9094 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7905.011 | 0.5456 | 0.0252 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7905.011 | 0.0213 | -0.9714 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7905.011 | 0.0057 | -0.9933 | 0.9066 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7906.011 | 0.5843 | 0.0068 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7906.011 | 1.2547 | 1.6723 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7906.011 | 0.5754 | -0.0126 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7906.011 | 0.9294 | 0.8216 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7906.011 | 1.1288 | 1.3347 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7906.011 | 1.1817 | 1.4754 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7906.011 | 0.6340 | 0.1177 | 0.7830 |