Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7906.011 | 0.0498 | -0.9566 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7906.011 | 0.0182 | -0.9880 | 0.7830 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7907.011 | 0.9179 | 0.8822 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7907.011 | 1.1767 | 1.2443 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7907.011 | 0.9244 | 0.8916 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7907.011 | 1.0656 | 1.0920 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7907.011 | 1.1152 | 1.1606 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7907.011 | 1.0124 | 1.0175 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7907.011 | 0.8088 | 0.7209 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7907.011 | 0.0371 | -0.8059 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7907.011 | 0.0106 | -0.9200 | 1.4119 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7909.075 | 0.8916 | 0.8556 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7909.075 | 1.1815 | 1.2303 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7909.075 | 0.8832 | 0.8441 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7909.075 | 1.0340 | 1.0441 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7909.075 | 1.0434 | 1.0563 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7909.075 | 0.9573 | 0.9438 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7909.075 | 0.6453 | 0.5022 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7909.075 | 0.0594 | -0.6837 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7909.075 | 0.0114 | -0.8926 | 1.5307 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9759.011 | 0.9847 | 0.9747 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9759.011 | 1.0374 | 1.0614 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9759.011 | 0.9496 | 0.9167 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9759.011 | 1.0194 | 1.0318 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9759.011 | 0.9763 | 0.9610 | 1.2153 |