Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.00345	uM	7870.011	1.0261	1.0244	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.0172	uM	7870.011	1.0118	1.0111	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.0862	uM	7870.011	1.0192	1.0180	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.431	uM	7870.011	1.0357	1.0332	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	2.15	uM	7870.011	0.9844	0.9853	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	10.8	uM	7870.011	0.8849	0.8882	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	53.9	uM	7870.011	0.6847	0.6737	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	269	uM	7870.011	0.1105	-0.2901	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	1350	uM	7870.011	0.0075	-0.7997	2.1270
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.00345	uM	9551.011	1.0427	1.0304	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.0172	uM	9551.011	1.0171	1.0122	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.0862	uM	9551.011	1.0060	1.0043	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	0.431	uM	9551.011	1.0573	1.0406	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	2.15	uM	9551.011	0.9969	0.9978	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	10.8	uM	9551.011	0.9404	0.9562	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	53.9	uM	9551.011	0.7276	0.7834	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	269	uM	9551.011	0.4762	0.5307	2.7742
MCF 10A	NM	Basal B	Carboplatin	DNA cross-linker	DNA cross-linker	1350	uM	9551.011	0.0069	-0.6668	2.7742
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	0.00345	uM	9566.011	0.9912	0.9925	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	0.0172	uM	9566.011	1.0390	1.0330	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	0.0862	uM	9566.011	0.9841	0.9863	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	0.431	uM	9566.011	1.0395	1.0334	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	2.15	uM	9566.011	0.9705	0.9745	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	10.8	uM	9566.011	0.8793	0.8929	2.3358
MCF 10F	NM	-	Carboplatin	DNA cross-linker	DNA cross-linker	53.9	uM	9566.011	0.4908	0.4747	2.3358

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)