Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7863.011 | 0.9677 | 0.9678 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7863.011 | 0.8554 | 0.8514 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7863.011 | 0.7664 | 0.7536 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7863.011 | 0.0172 | -0.7310 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7863.011 | 0.0110 | -0.7849 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7864.011 | 0.9947 | 0.9929 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7864.011 | 0.9729 | 0.9632 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7864.011 | 0.9949 | 0.9931 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7864.011 | 0.9669 | 0.9551 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7864.011 | 0.8413 | 0.7801 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7864.011 | 0.7518 | 0.6500 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7864.011 | 0.8210 | 0.7509 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7864.011 | 0.0179 | -0.8673 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7864.011 | 0.0108 | -0.9059 | 1.4831 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9511.021 | 1.0101 | 1.0150 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9511.021 | 1.0678 | 1.0999 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9511.021 | 1.0281 | 1.0416 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9511.021 | 1.0514 | 1.0758 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9511.021 | 0.9808 | 0.9715 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9511.021 | 0.9558 | 0.9340 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9511.021 | 0.8385 | 0.7548 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9511.021 | 0.0835 | -0.6837 | 1.3466 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9511.021 | 0.0252 | -0.8699 | 1.3466 | |
| LY2 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9536.011 | 1.0016 | 1.0025 | 1.2640 | |
| LY2 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9536.011 | 1.0789 | 1.1239 | 1.2640 |