Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9294.011 | 0.9577 | 0.8844 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9294.011 | 0.5252 | -0.1768 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9294.011 | 0.0514 | -0.9666 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10031.021 | 1.0059 | 1.0141 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10031.021 | 1.0763 | 1.1817 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10031.021 | 1.0462 | 1.1098 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10031.021 | 1.0423 | 1.1006 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10031.021 | 1.0358 | 1.0851 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10031.021 | 1.0677 | 1.1612 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10031.021 | 0.9505 | 0.8834 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10031.021 | 0.5126 | -0.0932 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10031.021 | 0.0888 | -0.8861 | 0.8450 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7825.011 | 0.9128 | 0.9078 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7825.011 | 1.0681 | 1.0693 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7825.011 | 0.9170 | 0.9123 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7825.011 | 1.0351 | 1.0361 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7825.011 | 1.0355 | 1.0364 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7825.011 | 0.8888 | 0.8817 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7825.011 | 0.6486 | 0.5987 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7825.011 | 0.2880 | 0.0505 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7825.011 | 0.0973 | -0.4006 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9347.011 | 0.9679 | 0.9612 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9347.011 | 1.0348 | 1.0415 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9347.011 | 0.9921 | 0.9905 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9347.011 | 1.0237 | 1.0283 | 1.6648 |