Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9347.011 | 1.0906 | 1.1070 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9347.011 | 0.9771 | 0.9724 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9347.011 | 0.8476 | 0.8108 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9347.011 | 0.5740 | 0.4330 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9347.011 | 0.3129 | -0.0049 | 1.6648 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7829.011 | 0.9657 | 0.9631 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7829.011 | 1.0373 | 1.0394 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7829.011 | 0.9584 | 0.9552 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7829.011 | 1.0110 | 1.0117 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7829.011 | 0.9358 | 0.9305 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7829.011 | 0.6560 | 0.5972 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7829.011 | 0.2346 | -0.0772 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7829.011 | 0.0121 | -0.8104 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7829.011 | 0.0063 | -0.8657 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9376.011 | 1.0347 | 1.0436 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9376.011 | 1.0110 | 1.0139 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9376.011 | 1.0566 | 1.0708 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9376.011 | 1.0135 | 1.0170 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9376.011 | 1.0379 | 1.0477 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9376.011 | 0.7829 | 0.7131 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9376.011 | 0.2937 | -0.0787 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9376.011 | 0.0162 | -0.8524 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9376.011 | 0.0125 | -0.8747 | 1.5809 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7832.011 | 0.9735 | 0.9630 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7832.011 | 0.9260 | 0.8959 | 1.4385 |