Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9157.021 | 0.9729 | 0.9464 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9157.021 | 0.5881 | 0.1830 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9157.021 | 0.1383 | -0.7173 | 1.0111 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9158.12 | 1.0399 | 1.1121 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9158.12 | 1.0512 | 1.1442 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9158.12 | 1.0963 | 1.2735 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9158.12 | 1.0787 | 1.2228 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9158.12 | 0.8810 | 0.6764 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9158.12 | 1.1196 | 1.3409 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9158.12 | 0.9238 | 0.7908 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9158.12 | 0.2757 | -0.6679 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9158.12 | 0.0759 | -0.9450 | 0.7176 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9163.011 | 1.0287 | 1.0924 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9163.011 | 0.9901 | 0.9684 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9163.011 | 1.0366 | 1.1180 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9163.011 | 1.0173 | 1.0556 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9163.011 | 1.0234 | 1.0753 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9163.011 | 1.0705 | 1.2298 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9163.011 | 0.9188 | 0.7470 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9163.011 | 0.5041 | -0.3297 | 0.6266 | |
| BT-474 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9163.011 | 0.0812 | -0.9636 | 0.6266 | |
| BT-483 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9186.119 | 1.0520 | 1.2254 | 0.4743 | |
| BT-483 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9186.119 | 1.0457 | 1.1976 | 0.4743 | |
| BT-483 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9186.119 | 1.0302 | 1.1296 | 0.4743 | |
| BT-483 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9186.119 | 0.9603 | 0.8361 | 0.4743 |