Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7898.011 | 1.0539 | 1.1038 | 1.0373 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7898.011 | 0.9734 | 0.9486 | 1.0373 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7898.011 | 0.7686 | 0.5519 | 1.0373 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7898.011 | 0.3740 | -0.2251 | 1.0373 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7898.011 | 0.1236 | -0.7335 | 1.0373 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7900.011 | 1.1005 | 1.3477 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7900.011 | 1.1428 | 1.5006 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7900.011 | 0.6105 | -0.1240 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7900.011 | 1.4691 | 2.8064 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7900.011 | 1.3986 | 2.5055 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7900.011 | 1.0555 | 1.1891 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7900.011 | 0.8875 | 0.6379 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7900.011 | 0.2738 | -0.7710 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7900.011 | 0.1246 | -0.9386 | 0.5977 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7902.075 | 0.9773 | 0.9767 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7902.075 | 1.2274 | 1.2206 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7902.075 | 0.8149 | 0.8016 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7902.075 | 1.0599 | 1.0603 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7902.075 | 1.0750 | 1.0752 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7902.075 | 0.8952 | 0.8901 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7902.075 | 0.7459 | 0.7219 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7902.075 | 0.3607 | 0.1883 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7902.075 | 0.0849 | -0.4322 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10266.011 | 1.0172 | 1.0500 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10266.011 | 1.1525 | 1.4570 | 0.6895 |