Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10875.072 | 0.6838 | 0.2406 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10875.072 | 0.4896 | -0.1848 | 0.7958 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7530.073 | 0.9750 | 0.9772 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7530.073 | 0.9548 | 0.9585 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7530.073 | 0.9614 | 0.9646 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7530.073 | 0.9804 | 0.9822 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7530.073 | 0.9350 | 0.9400 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7530.073 | 0.9346 | 0.9396 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7530.073 | 0.8558 | 0.8638 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7530.073 | 0.9171 | 0.9231 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7530.073 | 0.1660 | -0.1135 | 2.2072 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10819.072 | 1.0344 | 1.0312 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10819.072 | 0.9155 | 0.9209 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10819.072 | 0.9382 | 0.9425 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10819.072 | 0.9254 | 0.9303 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10819.072 | 0.9283 | 0.9332 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10819.072 | 0.8704 | 0.8771 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10819.072 | 0.9136 | 0.9190 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10819.072 | 0.5327 | 0.4997 | 2.1878 | |
| SUM149PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10819.072 | 0.2253 | 0.0119 | 2.1878 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7531.073 | 1.1142 | 1.0629 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7531.073 | 0.9919 | 0.9954 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7531.073 | 0.9906 | 0.9946 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7531.073 | 1.0398 | 1.0225 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7531.073 | 1.2088 | 1.1117 | 3.4904 |