Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7527.072 | 1.0104 | 1.0108 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7527.072 | 0.9835 | 0.9828 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7527.072 | 0.9374 | 0.9340 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7527.072 | 1.0132 | 1.0137 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7527.072 | 0.9938 | 0.9935 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7527.072 | 0.9552 | 0.9530 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7527.072 | 0.9231 | 0.9187 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7527.072 | 0.8060 | 0.7883 | 1.9274 | |
| SK-BR-3 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7527.072 | 0.5498 | 0.4664 | 1.9274 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10381.072 | 1.0490 | 1.0786 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10381.072 | 1.0384 | 1.0616 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10381.072 | 1.0001 | 1.0002 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10381.072 | 1.0183 | 1.0294 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10381.072 | 1.0073 | 1.0118 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10381.072 | 1.0102 | 1.0165 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10381.072 | 1.0030 | 1.0049 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10381.072 | 0.7887 | 0.6518 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10381.072 | 0.6700 | 0.4484 | 1.2411 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10875.072 | 0.9835 | 0.9585 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10875.072 | 1.0478 | 1.1209 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10875.072 | 1.0276 | 1.0697 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10875.072 | 1.0801 | 1.2033 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10875.072 | 0.9477 | 0.8694 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10875.072 | 0.9919 | 0.9797 | 0.7958 | |
| SUM1315MO2 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10875.072 | 0.8966 | 0.7438 | 0.7958 |